14 year old female with Diabetic Ketoacidosis
14 year old diabetic female with shortness of breath
July 14, 2023
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Chief complaints
Rash over abdomen since 3 days
Shortness of breath since afternoon
Fever since afternoon
History of Present Illness
Patient was apparently asymptomatic 2 hours ago then she developed SOB, sudden in onset, grade - 4. No orthopnea and PND.No H/O chest pain, pedal edema, palpitations, excessive sweating, giddiness and wheezing
Fever since 8 hours, high grade associated with chills and rigor since 2 pm afternoon
Rash over the abdomen since 3 days, no itching or redness, watery discharge. Applied crushed paracetamol tablet on the rash
No H/O loose stools, pain abdomen, giddiness.
Dialy routine:
Wakes up at 6 am in the morning
Takes insulin at 7:15 am( 4 units of isophane and 6 units of HAI) and eats breakfast at 7:40 am
Starts to school at 7:50 am (travels via grandfather's bike)
Has Lunch at 12:30 pm
Comes home at 5 pm, eats snacks and goes to tution from 5 - 8 pm
Takes insulin at 8:15 pm (4 units of isophane and 6 units of HAI) and eats at around 8:40 pm
Sleeps at around 10 pm
Events on 13-07-23 :
Woke up at 6 am
Missed the morning dose of insulin and breakfast because she was late to school
Went to school at 8 am
Felt giddiness and told the Teacher about it. Teacher asked her to have some food
Refused to eat due to nausea
Had Vomiting at 11 pm - watery content
At 12:30 vomited once again - water content
Informed her grandfather and went home at 1 pm
At home she started developing SOB so didn't eat again
Went to local doctor due to SOB at 5 pm
She was put on O2 there and when it didn't resolve the doctor advice to go to higher centre
Came to kamineni at 7:30 pm
Past history
Patient is known case of Type 1 DM since 3 yrs
Diagnosed 3 yrs before when she complained of polyuria
After diagnosis she used to take 4+4 HAI and Isophane in the morning and night. And 2+2 HAI and isophane in the afternoon.
After one year, on a regular checkup, her sugars weren't controlled, So she was advice to take HAI - 6 IU, Isophane - 4 IU 20 mins before eating since 2 years
H/O right humerus fracture 1 year back (skid and fell from bike while going to school) Treated conservatively with cast for 1 month
Family history
H/O Type 1 DM in father. (Diagnosed at 12 years age)
Has been on insulin treatment since then
Father underwent dialysis due to CKD 7 yrs back and died 5 yrs back
General examination
No signs of pallor, icterus, cyanosis, clubbing, Lymphadenopathy and pedal edema
Vitals:
PR : 158 bpm
BP : 110/60 mmhg
Temperature : 98.6 F
RR : 54 cpm
Spo2 : 98%
Systemic examination
RESPIRATORY SYSTEM EXAMINATION
Bilateral air entry +
Normal vesicular breath sounds
Trachea - central
No added sounds
CVS EXAMINATION
S1, S2 heard
No murmurs
ABDOMEN EXAMINATION
No tenderness
No organomegaly
Bowel sounds - present
Rash on the abdomen
CNS EXAMINATION
Higher mental functions - normal
Cranial nerve examination - normal
Sensory and motor system - normal
No signs of meningeal irritation
Investigations
Urine for KETONE BODIES : positive
Random Blood Sugar : 624 mg/dl
Hemogram:
Renal Function Test
Liver Function Test
Complete Urine Examination
Diagnosis: Diabetic ketoacidosis with type 1 DM
Treatment
1. IV fluids 40 ml bolus followed by NS 150 ml/hr
2. INJ HAI - 8 IU / stat
3. Inj HAI 40 IU in 39 ml NS @ 6 ml / hr (Inc/Dec according to GRBS)
4. IV fluids - 5D@50 ml/hr if GRBS<200 mg/ dl
5. Input/Output charting